Nuclear Medicine Cardiac
Nuclear Medicine Menu
General | Cardiac
- What is Cardiac Nuclear Medicine?
- What are some common uses of the procedure?
- How should I prepare for the procedure?
- What does the equipment look like?
- How does the procedure work?
- How is the procedure performed?
- What will I experience during the procedure?
- Who interprets the results and how do I get them?
- What are the benefits vs. risks?
- What are the limitations of Cardiac Nuclear Medicine?
- Which Health Diagnostics facilities offer this service?

What is Cardiac Nuclear Medicine?
Nuclear medicine is a healthcare specialty involving the use
of radioactive compounds to perform diagnostic imaging examinations
that can lead to the effective treatment of many diseases. Although
nuclear medicine is often considered an independent discipline,
it is closely related to radiology in that radiation is used
to develop images of human anatomy.
Cardiac nuclear medicine refers to these diagnostic
tests that are used to examine the anatomy and function of the
heart.
What are some common uses of the procedure?
Cardiac nuclear medicine tests are indicated for individuals
with unexplained chest pain or chest pain brought on by exercise
(called angina) to permit the early detection of heart disease.
The most common cardiac nuclear medicine procedure, called myocardial
perfusion scanning, enables the visualization of blood-flow patterns
to the heart walls. The test is important for evaluating the
presence and extent of suspected or known coronary artery disease
(blockages) as well as the results of previous injury to the
heart from a heart attack, called a myocardial infarction. It
also can be done to evaluate the results of bypass surgery or
other percutaneous revascularization procedures designed to restore
the blood supply to the heart.
Heart-wall movement and overall
heart function can be evaluated with cardiac gating, a technique
that synchronizes the images of the heart with different parts
of the cardiac cycle (contracting or relaxing) as determined
by an electrocardiogram (ECG), which records the electrical currents
that activate the heart muscle and cause it to pump.
How should I prepare for the
procedure?
You should avoid caffeine (coffee, tea, chocolate,
most soda) and smoking for 48 hours before the examination.
Avoid the following medications, which contain caffeine: Anacin,
Cafergot, Esgic, Excerdrine, Fioricet, Fiorinal, NoDoz, Norgesic,
Norgesic Forte, Synalgos DC, Wigraine and Vivarin. You should
not eat or drink anything except water 6 hours before the procedure.
Diabetic patients should not take medications prior to exam,
but should bring medication to appointment to take after. Do
not apply any creams, lotions or powder to your chest area on
the day of the exam. Wear comfortable, walking shoes and loose-fitting
clothes for your procedure. Bring a protein type snack and drink
with to have after the exercise portion of the exam.
What does the equipment look like?
The
imaging equipment, called a gamma camera or scintillation camera,
consists of specialized detectors enclosed within a metal housing.
The detector portion of the camera can be changed to a variety
of positions to obtain images of the body from different directions.
A nearby computer console, possibly in another room, is used to
develop the images of the heart.
How
does the procedure work?
Coronary arteries are best evaluated
by determining the changes in blood flow to the heart due to
exercising. Consequently, you will undergo a stress
test—most commonly through physical exercise—to
make your heart work harder than normal. Then you
will be given a radioactive compound, called a radiopharmaceutical
agent or tracer. This compound will collect in parts of your
heart with good blood flow and will give off gamma rays. The
gamma camera detects the rays. Subsequently, a computer following
a set of complicated mathematical formulas will construct images
of the heart based on the detected gamma rays.
How is the procedure performed?
For
the stress part of the examination, you will exercise by either
walking on a treadmill or pedaling a stationary bicycle for a few
minutes. While you exercise, the electrical activity of your heart
will be monitored by electrocardiography (ECG), and your blood
pressure will be measured frequently. Before you stop exercising,
you will be given the radiopharmaceutical through an IV leading
into a vein in your arm. The compound is given when the blood flow
to the heart is at its peak because of your exercising. This provides
the best opportunity to identify regions of the heart that are
not receiving adequate blood flow.
One minute later, you will stop exercising. Approximately
one half-hour later, as you lay on an examining table,
the compound will have collected in your heart. The
gamma camera will then be used to obtain images.
The gamma camera likely will move slowly and automatically in
an arc over the front of your chest after it is positioned initially
by the technologist.
The images obtained after exercise must usually be
compared with images of your heart obtained after injection of
the same radiopharmaceutical while you are resting. This may
be performed before or after the exercise part of the examination,
depending on the protocol used. Comparison of the exercise and
resting images is done to determine whether coronary blood flow
has changed once you have rested and to check for coronary artery
disease.
If you are unable to use a treadmill or bicycle,
you will not exercise, but you will be given a drug that will
cause your heart to work as hard as if you had exercised. You
will then be given the radiopharmaceutical.
Immediately after the procedure, a diagnostic radiologist
with specialized training in nuclear medicine will check the
quality of the images to ensure that an optimal diagnostic study
has been performed.
What will
I experience during the procedure?
You may experience some minor discomfort from the intravenous
injection of the radiopharmaceutical.
You will be asked to exercise until you are either
too tired to continue or short of breath, or if you experience
chest pain, leg pain, or other discomfort that causes you to
want to stop.
If you are given a medication to increase blood flow
because you are unable to exercise, the medication may induce
a brief period of feeling anxious, dizzy, nauseous, shaky or
short of breath. In rare instances, if the side effects of the
medication are severe or make you too uncomfortable, other drugs
can be given to stop the effects.
Most patients can resume regular activities immediately
after the procedure. The radioactivity in your body will decrease
due to the natural process of radioactive decay. In addition,
radioactivity will decrease because the radiopharmaceutical passes
out of the body in the urine or stool.
Who interprets the results and how do I get them?
Generally, patients undergo a nuclear medicine examination because
a referring physician has recommended it. A physician who has
specialized training in nuclear medicine will interpret the images.
It usually takes one to three days to interpret, report, and
deliver the information to your referring physician. Your referring
physician will then inform you of the results.
What are the benefits vs. risks?
Benefits
- The functional information regarding blood flow to the heart and the pumping function of the heart is well demonstrated. This information may be used to determine what treatment or additional testing, if any, is needed.
- Computers are involved in the generation of the images, so measurements or quantification of function, as well as the determination of abnormalities, are possible.
- Because the procedure is generally performed according to standardized protocols, the type of examination done at one hospital is likely to be similar to that performed at other hospitals, making the information easy to understand or to transfer to all doctors who may be involved in your care.
Risks
- If you have coronary artery disease, it is possible that you could experience chest pain, or angina, when stress due to exercise or a drug is applied to your heart. However, your test will be carried out under the supervision of a specialist trained to monitor you and your heart by using information being provided by the electrocardiogram, by your heart rhythm, and by your blood pressure. If necessary, medication can be given for your chest pain. You will be monitored long enough to ensure that you are at your baseline; that is, the condition you were in when you came for the test.
- The use of a radioactive substance will result in exposure to a small amount of radiation to the heart and to the body. However, the amount of radioactivity administered is the smallest amount necessary to provide adequate images. Cardiac nuclear medicine procedures have been done for more than three decades, and no long-term adverse effects have been reported from such low-dose studies.
- Allergic reactions to radiopharmaceuticals can occur but are extremely rare.
- As with all radiologic procedures, it is important that you inform your physician and the technologist if you are pregnant. In general, exposure to radiation during pregnancy should be kept to a minimum. Depending on the nature of your medical problem, the cardiac nuclear medicine procedure may be postponed until after your pregnancy.
What are the limitations of Cardiac Nuclear Medicine?
Compared with most radiology studies, cardiac nuclear medicine
procedures are time-consuming. They involve either exercise or
the administration of a drug to increase blood flow to the heart,
obtaining gamma-camera images (usually two sets of images separated
by a few hours), and then computer manipulation of the information.
Depending on the exact procedure performed, the myocardial perfusion
scan takes between two and five hours. Occasionally, a patient
may be asked to return to the nuclear medicine department the
next day. An outpatient may be allowed to leave the hospital
between the two sets of images. An inpatient will usually return
to his or her hospital room between the imaging sessions.
Which Health Diagnostics facilities offer this service?
